Paradigm of Sudden Death Prevention in Hypertrophic Cardiomyopathy
نویسندگان
چکیده
منابع مشابه
Prevention of Sudden Death in Hypertrophic Cardiomyopathy
C ase presentation: A 14-yearold girl died suddenly and unexpectedly while exercising. Clinical and echocardiographic family screening identified hypertrophic cardiomyopathy (HCM) in her only sibling, an asymptomatic 17-year-old boy. In her brother, echocardiography showed extreme septal ventricular hypertrophy, 35 mm in thickness; left ventricular (LV) outflow obstruction was absent. Left atri...
متن کاملRisk stratification and prevention of sudden death in hypertrophic cardiomyopathy.
Sudden unexpected death, often occurring in young, asymptomatic patients, is the most devastating facet of the natural history of hypertrophic cardiomyopathy, and appears to be the consequence of primary ventricular tachyarrhythmias arising in an electrically unstable myocardial substrate characterized by disorganized cellular architecture, ischemia, cell death, and replacement scarring. Althou...
متن کاملHypertrophic cardiomyopathy: management, risk stratification, and prevention of sudden death.
http://heart.bmj.com/cgi/content/full/87/2/169 Updated information and services can be found at: These include: Data supplement http://heart.bmj.com/cgi/content/full/87/2/169/DC1 "Web only references" References http://heart.bmj.com/cgi/content/full/87/2/169#otherarticles 16 online articles that cite this article can be accessed at: http://heart.bmj.com/cgi/content/full/87/2/169#BIBL This artic...
متن کاملSudden cardiac death risk in hypertrophic cardiomyopathy.
It is well recognized that sudden cardiac death (SCD) is an infrequent, unpredictable, but catastrophic complication of hypertrophic cardiomyopathy (HCM). In population-based studies the overall SCD rate is 1% per year among patients with a clinical diagnosis of HCM. A crucial aspect of the management of patients with HCM is an assessment of each individual patient’s risk for SCD so that preven...
متن کاملSudden cardiac death in hypertrophic cardiomyopathy.
Introduction Hypertrophic cardiomyopathy (HCM) is a common disorder of cardiac muscle associated with sudden cardiac death (SCD). HCM is defined by increased left ventricular wall thickness or mass, in the absence of abnormal loading conditions to account for the observed abnormality. In most adults, the disease is inherited as an autosomal dominant trait and is caused by mutations in cardiac s...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2019
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.119.315159